Rusty Creek is a river in the Canadian province of Saskatchewan. The river's source is First Mustus Lake, which is a lake in Meadow Lake Provincial Park, and its mouth is along the course of the Waterhen River. It is a south flowing river and the entirety of its course is in Meadow Lake Provincial Park and the boreal forest ecozone. Rusty Creek is a tributary of Waterhen River, which is a major tributary of Beaver River of the Churchill River and in the Hudson Bay drainage basin.